سیکلوفسفامید: تفاوت میان نسخهها
محتوای حذفشده محتوای افزودهشده
Paiamshadi (بحث | مشارکتها) بدون خلاصۀ ویرایش |
قلی زادگان (بحث | مشارکتها) بدون خلاصۀ ویرایش |
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خط ۱:
{{Drugbox
| verifiedrevid = 459435450
| IUPAC_name = (''RS'')-''N'',''N''-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
| image = Cyclophosphamid.svg
| width = 150
| image2 = R-cyclophosphamide-from-xtal-1996-3D-balls.png
<!--Clinical data-->
| tradename = Lyophilizedcytoxan
| Drugs.com = {{drugs.com|monograph|cyclophosphamide}}
| MedlinePlus = a682080
| pregnancy_AU = D
| pregnancy_US = D
| pregnancy_category =
| legal_status = Rx-only
| dependency_liability =
| routes_of_administration = Oral, [[Intravenous therapy|intravenous]]
<!--Pharmacokinetic data-->
| bioavailability = >75% (oral)
| protein_bound = >60%
| metabolism = [[Liver|Hepatic]]
| elimination_half-life = 3-12 hours
| excretion = [[Kidney|Renal]]
<!--Chemical data-->
| C=7 | H=15 | Cl=2 | N=2 | O=2 | P=1
| molecular_weight = 261.086 [[Gram|g]]/[[Mole (unit)|mol]]
| smiles = O=P1(OCCCN1)N(CCCl)CCCl
| InChI = 1/C7H15Cl2N2O2P/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14/h1-7H2,(H,10,12)
| InChIKey = CMSMOCZEIVJLDB-UHFFFAOYAB
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = DB00531
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 6UXW23996M
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 4027
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D07760
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 88
| ChemSpiderID = 2804
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 50-18-0
| ATC_prefix=L01
| ATC_suffix=AA01
| ATC_supplemental=
| StdInChI = 1S/C7H15Cl2N2O2P/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14/h1-7H2,(H,10,12)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = CMSMOCZEIVJLDB-UHFFFAOYSA-N
| density =
| melting_point = 2
| boiling_point =
| solubility =
| specific_rotation =
| sec_combustion =
}}
'''سیکلوفسفامید''' {{انگلیسی|Cyclophosphamide}}
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