خانه
تصادفی
در نزدیکی
ورود
تنظیمات
کمک مالی
دربارهٔ ویکیپدیا
تکذیبنامهها
جستجو
الگو
:
PBB/10013
زبان
پیگیری
ویرایش
<
الگو:PBB
Histone deacetylase 6
Rendering based on
بانک داده پروتئین
3C5K
.
ساختارهای موجود
بانک داده پروتئین
Ortholog search:
PDBe
,
RCSB
فهرست کدهای شناسه PDB
3C5K
,
3GV4
,
3PHD
شاخصها
نماد ژن
HDAC6
; HD6
شناسههای بیرونی
OMIM
:
300272
MGI
:
1333752
HomoloGene
:
31353
ChEMBL
:
1865
GeneCards
:
HDAC6 Gene
EC number
3.5.1.98
هستیشناسی ژن
Molecular function
•
actin binding
•
histone deacetylase activity
•
protein binding
•
beta-catenin binding
•
microtubule binding
•
zinc ion binding
•
enzyme binding
•
polyubiquitin binding
•
NAD-dependent histone deacetylase activity (H3-K14 specific)
•
histone deacetylase binding
•
tubulin deacetylase activity
•
alpha-tubulin binding
•
NAD-dependent histone deacetylase activity (H3-K9 specific)
•
NAD-dependent histone deacetylase activity (H4-K16 specific)
•
tau protein binding
•
beta-tubulin binding
•
Hsp90 protein binding
•
dynein complex binding
•
NAD-dependent histone deacetylase activity (H3-K18 specific)
Cellular component
•
histone deacetylase complex
•
nucleus
•
nucleolus
•
cytoplasm
•
cytosol
•
microtubule
•
microtubule associated complex
•
cytoplasmic microtubule
•
caveola
•
inclusion body
•
aggresome
•
dynein complex
•
cell leading edge
•
perinuclear region of cytoplasm
Biological process
•
protein polyubiquitination
•
transcription, DNA-dependent
•
protein deacetylation
•
misfolded or incompletely synthesized protein catabolic process
•
intracellular protein transport
•
negative regulation of microtubule depolymerization
•
response to toxin
•
positive regulation of signal transduction
•
response to organic substance
•
regulation of receptor activity
•
positive regulation of epithelial cell migration
•
negative regulation of hydrogen peroxide metabolic process
•
positive regulation of receptor biosynthetic process
•
macroautophagy
•
histone deacetylation
•
lysosome localization
•
peptidyl-lysine deacetylation
•
cellular response to topologically incorrect protein
•
positive regulation of apoptotic process
•
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
•
protein complex disassembly
•
negative regulation of protein complex disassembly
•
negative regulation of proteolysis
•
negative regulation of transcription, DNA-dependent
•
negative regulation of oxidoreductase activity
•
response to misfolded protein
•
regulation of microtubule-based movement
•
regulation of androgen receptor signaling pathway
•
cellular response to hydrogen peroxide
•
aggresome assembly
•
polyubiquitinated misfolded protein transport
•
Hsp90 deacetylation
•
response to growth factor stimulus
•
cellular response to misfolded protein
•
positive regulation of chaperone-mediated protein complex assembly
•
tubulin deacetylation
Sources:
Amigo
/
QuickGO
الگوی بیان RNA
دادهای بیان مرجع بیشتر
اورتولوگ
گونهها
انسان
موش
آنتره
10013
15185
آنسامبل
ENSG00000094631
ENSMUSG00000031161
UniProt
Q9UBN7
Q9Z2V5
RefSeq (mRNA)
NM_006044.2
NM_001130416.1
RefSeq (protein)
NP_006035.2
NP_001123888.1
موقعیت (UCSC)
Chr X:
48.66 – 48.68 Mb
Chr X:
7.93 – 7.95 Mb
جستجوی
پابمد
[۱]
[۲]
ن
ب
و