خانه
تصادفی
در نزدیکی
ورود
تنظیمات
کمک مالی
دربارهٔ ویکیپدیا
تکذیبنامهها
جستجو
الگو
:
PBB/1027
زبان
پیگیری
ویرایش
<
الگو:PBB
Cyclin-dependent kinase inhibitor 1B (p27, Kip1)
PDB
rendering based on 1jsu.
ساختارهای موجود
بانک داده پروتئین
Ortholog search:
PDBe
,
RCSB
فهرست کدهای شناسه PDB
1H27
,
1JSU
,
2AST
شاخصها
نماد ژن
CDKN1B
; CDKN4; KIP1; MEN1B; MEN4; P27KIP1
شناسههای بیرونی
OMIM
:
600778
MGI
:
104565
HomoloGene
:
2999
GeneCards
:
CDKN1B Gene
هستیشناسی ژن
Molecular function
•
cyclin-dependent protein kinase inhibitor activity
•
transforming growth factor beta receptor, cytoplasmic mediator activity
•
protein binding
•
cysteine-type endopeptidase activator activity involved in apoptotic process
•
protein phosphatase binding
Cellular component
•
nucleus
•
nucleoplasm
•
cytoplasm
•
endosome
•
cytosol
Biological process
•
cell cycle checkpoint
•
regulation of cyclin-dependent protein kinase activity
•
G1 phase of mitotic cell cycle
•
G1/S transition of mitotic cell cycle
•
S phase of mitotic cell cycle
•
mitotic cell cycle
•
potassium ion transport
•
induction of apoptosis
•
activation of cysteine-type endopeptidase activity involved in apoptotic process
•
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
•
cell cycle arrest
•
epidermal growth factor receptor signaling pathway
•
sensory perception of sound
•
positive regulation of cell proliferation
•
negative regulation of cell proliferation
•
fibroblast growth factor receptor signaling pathway
•
positive regulation of cell death
•
negative regulation of cell growth
•
positive regulation of microtubule polymerization
•
negative regulation of kinase activity
•
negative regulation of phosphorylation
•
negative regulation of apoptotic process
•
positive regulation of protein catabolic process
•
negative regulation of cyclin-dependent protein kinase activity
•
negative regulation of transcription, DNA-dependent
•
negative regulation of mitotic cell cycle
•
nerve growth factor receptor signaling pathway
•
phosphatidylinositol-mediated signaling
•
autophagic cell death
•
inner ear development
•
negative regulation of cellular component movement
•
negative regulation of epithelial cell proliferation involved in prostate gland development
•
cellular response to antibiotic
•
cellular response to lithium ion
•
cellular response to organic cyclic compound
•
mitotic cell cycle arrest
Sources:
Amigo
/
QuickGO
الگوی بیان RNA
دادهای بیان مرجع بیشتر
اورتولوگ
گونهها
انسان
موش
آنتره
1027
12576
آنسامبل
ENSG00000111276
ENSMUSG00000003031
UniProt
P46527
P46414
RefSeq (mRNA)
NM_004064.3
NM_009875.4
RefSeq (protein)
NP_004055.1
NP_034005.2
موقعیت (UCSC)
Chr 12:
12.87 – 12.88 Mb
Chr 6:
134.92 – 134.93 Mb
جستجوی
پابمد
[۱]
[۲]
ن
ب
و