خانه
تصادفی
در نزدیکی
ورود
تنظیمات
کمک مالی
دربارهٔ ویکیپدیا
تکذیبنامهها
جستجو
الگو
:
PBB/10392
زبان
پیگیری
ویرایش
<
الگو:PBB
Nucleotide-binding oligomerization domain containing 1
PDB
rendering based on 2b1w.
ساختارهای موجود
بانک داده پروتئین
Ortholog search:
PDBe
,
RCSB
فهرست کدهای شناسه PDB
2B1W
,
2DBD
,
2NSN
,
2NZ7
,
4E9M
شاخصها
نماد ژن
NOD1
; CARD4; CLR7.1; NLRC1
شناسههای بیرونی
OMIM
:
605980
MGI
:
1341839
HomoloGene
:
4440
ChEMBL
:
1293222
GeneCards
:
NOD1 Gene
هستیشناسی ژن
Molecular function
•
protein binding
•
ATP binding
•
cysteine-type endopeptidase activator activity involved in apoptotic process
•
identical protein binding
•
protein homodimerization activity
•
peptidoglycan binding
•
CARD domain binding
Cellular component
•
cytoplasm
•
cytosol
•
basolateral plasma membrane
Biological process
•
activation of MAPK activity
•
toll-like receptor signaling pathway
•
positive regulation of dendritic cell antigen processing and presentation
•
MyD88-dependent toll-like receptor signaling pathway
•
MyD88-independent toll-like receptor signaling pathway
•
apoptotic process
•
induction of apoptosis
•
activation of cysteine-type endopeptidase activity involved in apoptotic process
•
defense response
•
inflammatory response
•
signal transduction
•
JNK cascade
•
Toll signaling pathway
•
detection of biotic stimulus
•
detection of bacterium
•
positive regulation of interleukin-6 production
•
positive regulation of tumor necrosis factor production
•
toll-like receptor 1 signaling pathway
•
toll-like receptor 2 signaling pathway
•
toll-like receptor 3 signaling pathway
•
toll-like receptor 4 signaling pathway
•
intracellular signal transduction
•
TRIF-dependent toll-like receptor signaling pathway
•
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
•
interleukin-8 biosynthetic process
•
defense response to bacterium
•
positive regulation of I-kappaB kinase/NF-kappaB cascade
•
innate immune response
•
positive regulation of JNK cascade
•
defense response to Gram-positive bacterium
•
positive regulation of NF-kappaB transcription factor activity
•
protein oligomerization
•
stress-activated MAPK cascade
•
positive regulation of ERK1 and ERK2 cascade
•
nucleotide-binding oligomerization domain containing signaling pathway
Sources:
Amigo
/
QuickGO
الگوی بیان RNA
دادهای بیان مرجع بیشتر
اورتولوگ
گونهها
انسان
موش
آنتره
10392
107607
آنسامبل
ENSG00000106100
ENSMUSG00000038058
UniProt
Q9Y239
Q8BHB0
RefSeq (mRNA)
NM_006092.2
NM_001171007.1
RefSeq (protein)
NP_006083.1
NP_001164478.1
موقعیت (UCSC)
Chr 7:
30.46 – 30.52 Mb
Chr 6:
54.92 – 54.97 Mb
جستجوی
پابمد
[۱]
[۲]
ن
ب
و