خانه
تصادفی
در نزدیکی
ورود
تنظیمات
کمک مالی
دربارهٔ ویکیپدیا
تکذیبنامهها
جستجو
الگو
:
PBB/10413
زبان
پیگیری
ویرایش
<
الگو:PBB
Yes-associated protein 1
PDB
rendering based on 1jmq.
ساختارهای موجود
بانک داده پروتئین
Ortholog search:
PDBe
,
RCSB
فهرست کدهای شناسه PDB
1JMQ
,
1K5R
,
1K9Q
,
1K9R
,
2LAW
,
2LAX
,
2LAY
,
3KYS
,
3MHR
شاخصها
نماد ژن
YAP1
; YAP; YAP2; YAP65; YKI
شناسههای بیرونی
OMIM
:
606608
MGI
:
103262
HomoloGene
:
4452
GeneCards
:
YAP1 Gene
هستیشناسی ژن
Molecular function
•
RNA polymerase II transcription factor binding transcription factor activity
•
chromatin binding
•
transcription coactivator activity
•
transcription corepressor activity
•
protein binding
•
transcription regulatory region DNA binding
•
proline-rich region binding
Cellular component
•
nucleus
•
nucleoplasm
•
transcription factor complex
•
cytoplasm
•
cytosol
Biological process
•
vasculogenesis
•
embryonic heart tube morphogenesis
•
transcription initiation from RNA polymerase II promoter
•
response to DNA damage stimulus
•
cell proliferation
•
positive regulation of cell proliferation
•
gene expression
•
regulation of keratinocyte proliferation
•
keratinocyte differentiation
•
negative regulation of epithelial cell differentiation
•
notochord development
•
somatic stem cell maintenance
•
hippo signaling cascade
•
negative regulation of apoptotic process
•
positive regulation of transcription from RNA polymerase II promoter
•
positive regulation of organ growth
•
paraxial mesoderm development
•
lateral mesoderm development
•
contact inhibition
•
cellular response to gamma radiation
•
regulation of stem cell proliferation
•
positive regulation of canonical Wnt receptor signaling pathway
Sources:
Amigo
/
QuickGO
الگوی بیان RNA
دادهای بیان مرجع بیشتر
اورتولوگ
گونهها
انسان
موش
آنتره
10413
22601
آنسامبل
ENSG00000137693
ENSMUSG00000053110
UniProt
P46937
P46938
RefSeq (mRNA)
NM_001130145.2
NM_001171147.1
RefSeq (protein)
NP_001123617.1
NP_001164618.1
موقعیت (UCSC)
Chr 11:
101.98 – 102.1 Mb
Chr 9:
7.93 – 8 Mb
جستجوی
پابمد
[۱]
[۲]
ن
ب
و