خانه
تصادفی
در نزدیکی
ورود
تنظیمات
کمک مالی
دربارهٔ ویکیپدیا
تکذیبنامهها
جستجو
الگو
:
PBB/51561
زبان
پیگیری
ویرایش
<
الگو:PBB
اینترلوکین ۲۳،زیرواحد آلفا p19
ارائه بر اساس
PDB
3D85
.
ساختارهای موجود
بانک داده پروتئین
Ortholog search:
PDBe
,
RCSB
فهرست کدهای شناسه PDB
3D85
,
3D87
,
3DUH
,
3QWR
,
4GRW
شاخصها
نماد ژن
IL23A
; IL-23; IL-23A; IL23P19; P19; SGRF
شناسههای بیرونی
OMIM
:
605580
MGI
:
1932410
HomoloGene
:
12832
GeneCards
:
IL23A Gene
هستیشناسی ژن
Molecular function
•
cytokine activity
•
interleukin-23 receptor binding
Cellular component
•
interleukin-23 complex
Biological process
•
positive regulation of T cell mediated cytotoxicity
•
positive regulation of defense response to virus by host
•
positive regulation of T-helper 1 type immune response
•
inflammatory response
•
positive regulation of activation of JAK2 kinase activity
•
negative regulation of interleukin-10 production
•
positive regulation of granulocyte macrophage colony-stimulating factor production
•
positive regulation of interferon-gamma production
•
positive regulation of interleukin-10 production
•
positive regulation of interleukin-12 production
•
positive regulation of interleukin-17 production
•
positive regulation of tumor necrosis factor production
•
positive regulation of natural killer cell activation
•
positive regulation of natural killer cell proliferation
•
positive regulation of tissue remodeling
•
T cell proliferation
•
positive regulation of T cell proliferation
•
positive regulation of activated T cell proliferation
•
positive regulation of NF-kappaB import into nucleus
•
regulation of tyrosine phosphorylation of Stat1 protein
•
positive regulation of tyrosine phosphorylation of Stat3 protein
•
positive regulation of tyrosine phosphorylation of Stat4 protein
•
positive regulation of tyrosine phosphorylation of Stat5 protein
•
positive regulation of memory T cell differentiation
•
innate immune response
•
positive regulation of osteoclast differentiation
•
positive regulation of transcription from RNA polymerase II promoter
•
tissue remodeling
•
positive regulation of inflammatory response
•
defense response to Gram-negative bacterium
•
positive regulation of NK T cell activation
•
positive regulation of NK T cell proliferation
•
defense response to virus
•
positive regulation of neutrophil chemotaxis
•
positive regulation of T-helper 17 type immune response
•
positive regulation of T-helper 17 cell lineage commitment
Sources:
Amigo
/
QuickGO
الگوی بیان RNA
دادهای بیان مرجع بیشتر
اورتولوگ
گونهها
انسان
موش
آنتره
51561
83430
آنسامبل
ENSG00000110944
ENSMUSG00000025383
UniProt
Q9NPF7
Q9EQ14
RefSeq (mRNA)
NM_016584
NM_031252
RefSeq (protein)
NP_057668
NP_112542
موقعیت (UCSC)
Chr 12:
56.73 – 56.73 Mb
Chr 10:
128.3 – 128.3 Mb
جستجوی
پابمد
[۱]
[۲]
ن
ب
و