وارفارین: تفاوت میان نسخهها
محتوای حذفشده محتوای افزودهشده
جز ربات: مرتبسازی ردهها؛ زیباسازی |
قلی زادگان (بحث | مشارکتها) بدون خلاصۀ ویرایش |
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خط ۱:
{{drugbox | Verifiedfields = changed
| verifiedrevid = 460939157
| IUPAC_name = (''RS'')-4-hydroxy- 3-(3- oxo- 1-phenylbutyl)- 2''H''- chromen- 2-one
| image = Warfarin.svg
| image2 = Warfarin-from-xtal-3D-balls.png
<!--Clinical data-->
| tradename = Coumadin
| Drugs.com = {{drugs.com|monograph|coumadin}}
| MedlinePlus = a682277
| pregnancy_AU = D
| pregnancy_US = X
| legal_AU = S4
| legal_UK = POM
| legal_US = Rx-only
| routes_of_administration = Oral or [[intravenous therapy|intravenous]]
<!--Pharmacokinetic data-->
| bioavailability = 100%
| protein_bound = 99.5%
| metabolism = Hepatic: [[CYP2C9]], [[CYP2C19|2C19]], 2C8, 2C18, [[CYP1A2|1A2]] and [[CYP3A4|3A4]]
| elimination_half-life = 40 hours
| excretion = [[Kidney|Renal]] (92%)
<!--Identifiers-->
| CASNo_Ref = {{cascite|correct|CAS}}
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 81-81-2
| ATC_prefix = B01
| ATC_suffix = AA03
| PubChem = 6691
| DrugBank_Ref = {{drugbankcite|changed|drugbank}}
| DrugBank = DB00682
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 10442445
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 5Q7ZVV76EI
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D08682
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 10033
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 1464
<!--Chemical data-->
| C=19 | H=16 | O=4
| molecular_weight = 308.33 g/mol
| smiles = CC(=O)CC(C\1=C(/O)c2ccccc2OC/1=O)c3ccccc3
| InChI = 1/C19H16O4/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22/h2-10,15,21H,11H2,1H3
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C19H16O4/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22/h2-10,15,21H,11H2,1H3
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = PJVWKTKQMONHTI-UHFFFAOYSA-N
}}
'''وارفارین''' {{انگلیسی| Warfarin}} یا '''کمادین''' {{انگلیسی|Coumadin}}
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