فاکتور پاسخ سرم

SRF
ساختارهای موجود
PDB	جستجوی هم‌ساخت‌شناسی: PDBe RCSB
فهرست شناسه‌های PDB
	1HBX, 1K6O, 1SRS
معین‌کننده‌ها
نام‌های دیگر	SRF, MCM1, serum response factor
شناسه‌های بیرونی	OMIM: 600589 MGI: 106658 HomoloGene: 31135 GeneCards: SRF
موقعیت ژن (موش)
کروموزوم	کروموزوم ۱۷ (موش)
پایان	46,867,101 bp
الگوی گسترش RNA
	; ;
	More reference expression data
هستی‌شناسی ژن
عملکرد ملکولی	• protein dimerization activity; • GO:0001131، GO:0001151، GO:0001130، GO:0001204 DNA-binding transcription factor activity; • GO:0001077، GO:0001212، GO:0001213، GO:0001211، GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific; • GO:0000983 RNA polymerase II general transcription initiation factor activity; • primary miRNA binding; • transcription factor binding; • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding; • protein homodimerization activity; • serum response element binding; • chromatin binding; • GO:0001948، GO:0016582 پیوند پروتئینی; • DNA binding; • sequence-specific DNA binding; • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; • chromatin DNA binding; • transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding; • GO:0001158 cis-regulatory region sequence-specific DNA binding; • GO:0001200، GO:0001133، GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific; • histone deacetylase binding; • RNA polymerase II-specific DNA-binding transcription factor binding;
ترکیبات سلولی	• سیتوپلاسم; • هسته یاخته; • نوکلئوپلاسم;
فرایند زیستی	• dorsal aorta morphogenesis; • bronchus cartilage development; • muscle cell cellular homeostasis; • lung smooth muscle development; • regulation of water loss via skin; • transcription by RNA polymerase II; • stress fiber assembly; • cell migration involved in sprouting angiogenesis; • platelet activation; • cardiac myofibril assembly; • heart looping; • پیرشدگی سلول; • face development; • regulation of cell adhesion; • long-term depression; • neuron projection development; • morphogenesis of an epithelial sheet; • positive regulation of filopodium assembly; • primitive streak formation; • cellular response to glucose stimulus; • negative regulation of cell population proliferation; • response to cytokine; • GO:0009373 regulation of transcription, DNA-templated; • heart trabecula formation; • actin filament organization; • thymus development; • angiogenesis involved in wound healing; • ترومبوپوئز; • neuron development; • in utero embryonic development; • transcription, DNA-templated; • GO:0060469، GO:0009371 positive regulation of transcription, DNA-templated; • heart development; • positive regulation of cell differentiation; • branching involved in blood vessel morphogenesis; • positive regulation of axon extension; • positive regulation of smooth muscle contraction; • trachea cartilage development; • response to toxic substance; • positive regulation of pri-miRNA transcription by RNA polymerase II; • positive regulation of transcription by glucose; • regulation of smooth muscle cell differentiation; • epithelial structure maintenance; • associative learning; • skin morphogenesis; • positive regulation of DNA-binding transcription factor activity; • epithelial cell-cell adhesion; • neuron migration; • positive regulation of transcription initiation from RNA polymerase II promoter; • eyelid development in camera-type eye; • thyroid gland development; • negative regulation of amyloid-beta clearance; • negative regulation of cell migration; • developmental growth; • hematopoietic stem cell differentiation; • لایه‌زایی; • trophectodermal cell differentiation; • positive thymic T cell selection; • response to hormone; • cell-matrix adhesion; • sarcomere organization; • actin cytoskeleton organization; • megakaryocyte development; • response to hypoxia; • lung morphogenesis; • mesoderm formation; • cardiac vascular smooth muscle cell differentiation; • mRNA transcription by RNA polymerase II; • multicellular organism development; • tangential migration from the subventricular zone to the olfactory bulb; • حافظه بلندمدت; • contractile actin filament bundle assembly; • bicellular tight junction assembly; • leukocyte differentiation; • hippocampus development; • GO:0003257، GO:0010735، GO:1901228، GO:1900622، GO:1904488 positive regulation of transcription by RNA polymerase II; • erythrocyte development; • negative regulation of pri-miRNA transcription by RNA polymerase II; • forebrain development; • cell-cell adhesion;
	منابع: آمیگو / کوئیک‌گو
هم‌ساخت‌شناسی
	6722
	20807
	ENSG00000112658
	ENSMUSG00000015605
	P11831
	Q9JM73
	NM_001292001، XM_047419268 NM_003131، NM_001292001، XM_047419268
	XM_006523957، XM_011246336 NM_020493، XM_006523957، XM_011246336
	NP_003122 NP_001278930، NP_003122; NP_003122.1
	XP_006524020، XP_011244638 NP_065239، XP_006524020، XP_011244638
	ویکی‌داده
مشاهده/ویرایش انسان	مشاهده/ویرایش موش