JUNB

فاکتور رونویسی jun-B (انگلیسی: Transcription factor jun-B) یک پروتئین است که در انسان توسط ژن «JUNB» کدگذاری می‌شود. این پروتئین یک فاکتور رونویسی است که در تنظیم فعالیت برخی ژن‌ها بدنبال تحریک توسط فاکتور رشد نقش دارد.

JUNB
معین‌کننده‌ها
نام‌های دیگر	JUNB, AP-1, JunB proto-oncogene, AP-1 transcription factor subunit
شناسه‌های بیرونی	OMIM: 165161 MGI: 96647 HomoloGene: 7390 GeneCards: JUNB
موقعیت ژن (موش) کروموزوم کروموزوم ۸ (موش) نوار 8 C3|8 41.41 cM شروع 85,701,113 bp پایان 85,705,347 bp
الگوی گسترش RNA More reference expression data
هستی‌شناسی ژن عملکرد ملکولی • DNA binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding • GO:0001106 transcription corepressor activity • GO:0001131، GO:0001151، GO:0001130، GO:0001204 DNA-binding transcription factor activity • GO:0001105 transcription coactivator activity • GO:0001077، GO:0001212، GO:0001213، GO:0001211، GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • transcription factor binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001948، GO:0016582 پیوند پروتئینی • GO:0001200، GO:0001133، GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific ترکیبات سلولی • نوکلئوپلاسم • کروماتین • هسته یاخته • transcription factor AP-1 complex • transcription regulator complex فرایند زیستی • cellular response to calcium ion • GO:0009373 regulation of transcription, DNA-templated • GO:0044324، GO:0003256، GO:1901213، GO:0046019، GO:0046020، GO:1900094، GO:0061216، GO:0060994، GO:1902064، GO:0003258، GO:0072212 regulation of transcription by RNA polymerase II • regulation of cell death • osteoclast differentiation • labyrinthine layer blood vessel development • in utero embryonic development • GO:1901227 negative regulation of transcription by RNA polymerase II • transcription by RNA polymerase II • regulation of cell cycle • vasculogenesis • embryonic process involved in female pregnancy • response to lipopolysaccharide • decidualization • regulation of cell population proliferation • trophectodermal cell differentiation • osteoblast differentiation • positive regulation of cell differentiation • response to radiation • osteoblast proliferation • GO:0006928 cellular process • response to cAMP • response to mechanical stimulus • transcription, DNA-templated • cellular response to hormone stimulus • response to cytokine • GO:0003257، GO:0010735، GO:1901228، GO:1900622، GO:1904488 positive regulation of transcription by RNA polymerase II • cytokine-mediated signaling pathway • response to organic substance منابع: آمیگو / کوئیک‌گو
هم‌ساخت‌شناسی
گونه‌ها	انسان	موش
Entrez	3726	16477
آنسامبل	ENSG00000171223	ENSMUSG00000052837
یونی‌پروت	P17275	P09450
RefSeq (mRNA)	NM_002229	NM_008416
RefSeq (پروتئین)	NP_002220	NP_032442
موقعیت (UCSC)	ن/م	Chr : 85.7 – 85.71 Mb
جستجوی PubMed
ویکی‌داده
مشاهده/ویرایش انسان مشاهده/ویرایش موش

این پروتئین به توالیِ 5'-TGA[CG]TCA-3' در دی‌ان‌ای اتصال می‌یابد.

منابع

• مشارکت‌کنندگان ویکی‌پدیا. «JUNB». در دانشنامهٔ ویکی‌پدیای انگلیسی، بازبینی‌شده در ۱۸ مارس ۲۰۱۸.

بیشتر بخوانید

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• JUNB protein, human در سرعنوان‌های موضوعی پزشکی (MeSH) در کتابخانهٔ ملی پزشکی ایالات متحدهٔ آمریکا