گیرنده گامای رتینوئیک اسید

گیرنده گامای رتینوئیک اسید (انگلیسی: Retinoic acid receptor gamma) یا به اختصار RAR-γ، یک پروتئین است که در انسان توسط ژن «RARG» کُدگذاری می‌شود.

RARG
ساختارهای موجود PDB جستجوی هم‌ساخت‌شناسی: H3BMH6 PDBe H3BMH6 RCSB فهرست شناسه‌های PDB 1EXA, 1EXX, 1FCX, 1FCY, 1FCZ, 1FD0, 2LBD, 3LBD, 4LBD
معین‌کننده‌ها
نام‌های دیگر	RARG, NR1B3, RARC, retinoic acid receptor gamma, RARgamma
شناسه‌های بیرونی	OMIM: 180190 MGI: 97858 HomoloGene: 20263 GeneCards: RARG
موقعیت ژن (موش) کروموزوم کروموزوم ۱۵ (موش) نوار 15 F2|15 57.4 cM شروع 102,143,373 bp پایان 102,165,952 bp
هستی‌شناسی ژن عملکرد ملکولی • sequence-specific DNA binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding • zinc ion binding • metal ion binding • steroid hormone receptor activity • GO:0001948، GO:0016582 پیوند پروتئینی • GO:0001131، GO:0001151، GO:0001130، GO:0001204 DNA-binding transcription factor activity • DNA binding • retinoid X receptor binding • GO:0001200، GO:0001133، GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • GO:0000975 transcription cis-regulatory region binding • transcription factor binding • nuclear receptor coactivator activity • signaling receptor activity • GO:0038050، GO:0004886، GO:0038051 nuclear receptor activity ترکیبات سلولی • integral component of membrane • نوکلئوپلاسم • هسته یاخته • transcription regulator complex • RNA polymerase II transcription regulator complex فرایند زیستی • regulation of cell size • growth plate cartilage development • cellular response to retinoic acid • gland development • GO:0009373 regulation of transcription, DNA-templated • negative regulation of cartilage development • response to retinoic acid • multicellular organism growth • negative regulation of cell differentiation • bone morphogenesis • chondrocyte development • negative regulation of apoptotic process • retinal pigment epithelium development • transcription, DNA-templated • epithelium development • embryonic camera-type eye development • reproductive structure development • limb development • face development • neural tube closure • negative regulation of chondrocyte differentiation • Harderian gland development • prostate gland epithelium morphogenesis • regulation of myelination • GO:1901313 positive regulation of gene expression • retina development in camera-type eye • positive regulation of cell population proliferation • growth plate cartilage chondrocyte growth • canonical Wnt signaling pathway • ساماندهی بیان ژن • camera-type eye development • transcription initiation from RNA polymerase II promoter • regulation of myeloid cell differentiation • bone development • trachea cartilage development • anterior/posterior pattern specification • glandular epithelial cell development • steroid hormone mediated signaling pathway • GO:1901227 negative regulation of transcription by RNA polymerase II • GO:0003257، GO:0010735، GO:1901228، GO:1900622، GO:1904488 positive regulation of transcription by RNA polymerase II • embryonic hindlimb morphogenesis • retinoic acid receptor signaling pathway • negative regulation of cell population proliferation • embryonic eye morphogenesis • positive regulation of apoptotic process • positive regulation of programmed cell death • cellular response to leukemia inhibitory factor • multicellular organism development • hormone-mediated signaling pathway • دگرگونی یاخته‌ • response to lipid منابع: آمیگو / کوئیک‌گو
هم‌ساخت‌شناسی
گونه‌ها	انسان	موش
Entrez	5916	19411
آنسامبل	ENSG00000172819	ENSMUSG00000001288
یونی‌پروت	H3BMH6 P13631، H3BMH6	P18911
RefSeq (mRNA)	NM_001042728، NM_001243730، NM_001243731، NM_001243732 NM_000966، NM_001042728، NM_001243730، NM_001243731، NM_001243732	NM_011244، XM_006520650 NM_001042727، NM_011244، XM_006520650
RefSeq (پروتئین)	NP_001036193، NP_001230659، NP_001230660، NP_001230661، XP_024304880، XP_024304881، XP_024304882 NP_000957، NP_001036193، NP_001230659، NP_001230660، NP_001230661، XP_024304880، XP_024304881، XP_024304882	NP_035374، XP_006520713 NP_001036192، NP_035374، XP_006520713
موقعیت (UCSC)	ن/م	Chr : 102.14 – 102.17 Mb
جستجوی PubMed
ویکی‌داده
مشاهده/ویرایش انسان مشاهده/ویرایش موش

این پروتئین، یک گیرنده هسته‌ای، و یکی از انواع گیرنده‌های رتینوئیک اسید است.

منابع

• مشارکت‌کنندگان ویکی‌پدیا. «Retinoic acid receptor gamma». در دانشنامهٔ ویکی‌پدیای انگلیسی، بازبینی‌شده در ۳ فوریه ۲۰۲۰.

برای مطالعهٔ بیشتر

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